About Transaldolase
Transaldolase (TALDO1) is a protein
from Homo sapiens identified by UniProt accession
P37837, 337 residues long.
MolForge cross-references it against 0 known binders and
198 disease associations.
Target properties
| Protein name | Transaldolase |
|---|
| UniProt accession | P37837 |
|---|
| Gene | TALDO1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 337 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (198)
Diseases linked to this target (Open Targets).
- transaldolase deficiency · score 0.78
- Disorder of carbohydrate metabolism · score 0.46
- hydrops fetalis · score 0.37
- genetic disorder · score 0.19
- pulse pressure measurement · score 0.18
- cataract · score 0.12
- Microcephaly · score 0.12
- Severe global developmental delay · score 0.12
- azoospermia · score 0.09
- hepatocellular carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P37837-F1 | alphafold | PREDICTED | 95.60 | — |
Amino-acid sequence (337 residues)
MSSSPVKRQR MESALDQLKQ FTTVVADTGD FHAIDEYKPQ DATTNPSLIL AAAQMPAYQE LVEEAIAYGR KLGGSQEDQI KNAIDKLFVL FGAEILKKIP GRVSTEVDAR LSFDKDAMVA RARRLIELYK EAGISKDRIL IKLSSTWEGI QAGKELEEQH GIHCNMTLLF SFAQAVACAE AGVTLISPFV GRILDWHVAN TDKKSYEPLE DPGVKSVTKI YNYYKKFSYK TIVMGASFRN TGEIKALAGC DFLTISPKLL GELLQDNAKL VPVLSAKAAQ ASDLEKIHLD EKSFRWLHNE DQMAVEKLSD GIRKFAADAV KLERMLTERM FNAENGK
Explore Transaldolase with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets