Electron transfer flavoprotein subunit beta (ETFB)

About Electron transfer flavoprotein subunit beta

Electron transfer flavoprotein subunit beta (ETFB) is a protein from Homo sapiens identified by UniProt accession P38117, 255 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.

Target properties

Protein name	Electron transfer flavoprotein subunit beta
UniProt accession	P38117
Gene	ETFB
Organism	Homo sapiens
Length	255 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (99)

Diseases linked to this target (Open Targets).

multiple acyl-CoA dehydrogenase deficiency · score 0.82
Elevated circulating glutaric acid concentration · score 0.69
Glutaric aciduria · score 0.56
multiple acyl-CoA dehydrogenase deficiency, severe neonatal type · score 0.37
multiple acyl-CoA dehydrogenase deficiency, mild type · score 0.37
genetic disorder · score 0.19
chronic kidney disease · score 0.12
Behcet's syndrome · score 0.07
retinitis pigmentosa · score 0.07
Familial exudative vitreoretinopathy · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P38117-F1	alphafold	PREDICTED	96.16	—

Amino-acid sequence (255 residues)

MAELRVLVAV KRVIDYAVKI RVKPDRTGVV TDGVKHSMNP FCEIAVEEAV RLKEKKLVKE VIAVSCGPAQ CQETIRTALA MGADRGIHVE VPPAEAERLG PLQVARVLAK LAEKEKVDLV LLGKQAIDDD CNQTGQMTAG FLDWPQGTFA SQVTLEGDKL KVEREIDGGL ETLRLKLPAV VTADLRLNEP RYATLPNIMK AKKKKIEVIK PGDLGVDLTS KLSVISVEDP PQRTAGVKVE TTEDLVAKLK EIGRI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards