About Coilin
Coilin (COIL) is a protein
from Homo sapiens identified by UniProt accession
P38432, 576 residues long.
MolForge cross-references it against 0 known binders and
75 disease associations.
Target properties
| Protein name | Coilin |
|---|
| UniProt accession | P38432 |
|---|
| Gene | COIL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 576 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (75)
Diseases linked to this target (Open Targets).
- joint disease · score 0.18
- leukocyte count · score 0.13
- lymphocyte count · score 0.09
- hemoglobin measurement · score 0.09
- myeloid white cell count · score 0.08
- cancer · score 0.08
- mean platelet volume · score 0.05
- acute lymphoblastic leukemia · score 0.04
- infection · score 0.04
- infect · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P38432-F1 | alphafold | PREDICTED | 58.50 | — |
Amino-acid sequence (576 residues)
MAASETVRLR LQFDYPPPAT PHCTAFWLLV DLNRCRVVTD LISLIRQRFG FSSGAFLGLY LEGGLLPPAE SARLVRDNDC LRVKLEERGV AENSVVISNG DINLSLRKAK KRAFQLEEGE ETEPDCKYSK KHWKSRENNN NNEKVLDLEP KAVTDQTVSK KNKRKNKATC GTVGDDNEEA KRKSPKKKEK CEYKKKAKNP KSPKVQAVKD WANQRCSSPK GSARNSLVKA KRKGSVSVCS KESPSSSSES ESCDESISDG PSKVTLEARN SSEKLPTELS KEEPSTKNTT ADKLAIKLGF SLTPSKGKTS GTTSSSSDSS AESDDQCLMS SSTPECAAGF LKTVGLFAGR GRPGPGLSSQ TAGAAGWRRS GSNGGGQAPG ASPSVSLPAS LGRGWGREEN LFSWKGAKGR GMRGRGRGRG HPVSCVVNRS TDNQRQQQLN DVVKNSSTII QNPVETPKKD YSLLPLLAAA PQVGEKIAFK LLELTSSYSP DVSDYKEGRI LSHNPETQQV DIEILSSLPA LREPGKFDLV YHNENGAEVV EYAVTQESKI TVFWKELIDP RLIIESPSNT SSTEPA
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