Small ribosomal subunit protein eS19 (RPS19)

About Small ribosomal subunit protein eS19

Small ribosomal subunit protein eS19 (RPS19) is a protein from Homo sapiens identified by UniProt accession P39019, 145 residues long. MolForge cross-references it against 0 known binders and 259 disease associations.

Target properties

Protein name	Small ribosomal subunit protein eS19
UniProt accession	P39019
Gene	RPS19
Organism	Homo sapiens
Length	145 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (259)

Diseases linked to this target (Open Targets).

Blackfan-Diamond anemia · score 0.80
Diamond-Blackfan anemia · score 0.78
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
Short thumb · score 0.46
influenza · score 0.46
Abnormal radial ray morphology · score 0.37
severe acute respiratory syndrome · score 0.37
COVID-19 · score 0.37
neurodegenerative disease · score 0.30

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P39019-F1	alphafold	PREDICTED	92.01	—

Amino-acid sequence (145 residues)

MPGVTVKDVN QQEFVRALAA FLKKSGKLKV PEWVDTVKLA KHKELAPYDE NWFYTRAAST ARHLYLRGGA GVGSMTKIYG GRQRNGVMPS HFSRGSKSVA RRVLQALEGL KMVEKDQDGG RKLTPQGQRD LDRIAGQVAA ANKKH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards