B-cell antigen receptor complex-associated protein beta chain (CD79B)

About B-cell antigen receptor complex-associated protein beta chain

B-cell antigen receptor complex-associated protein beta chain (CD79B) is a protein from Homo sapiens identified by UniProt accession P40259, 229 residues long. MolForge cross-references it against 0 known binders and 334 disease associations.

Target properties

Protein name	B-cell antigen receptor complex-associated protein beta chain
UniProt accession	P40259
Gene	CD79B
Organism	Homo sapiens
Length	229 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P40259-F1	alphafold	PREDICTED	75.37	—

Amino-acid sequence (229 residues)

MARLALSPVP SHWMVALLLL LSAEPVPAAR SEDRYRNPKG SACSRIWQSP RFIARKRGFT VKMHCYMNSA SGNVSWLWKQ EMDENPQQLK LEKGRMEESQ NESLATLTIQ GIRFEDNGIY FCQQKCNNTS EVYQGCGTEL RVMGFSTLAQ LKQRNTLKDG IIMIQTLLII LFIIVPIFLL LDKDDSKAGM EEDHTYEGLD IDQTATYEDI VTLRTGEVKW SVGEHPGQE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards