Interferon alpha-inducible protein 27, mitochondrial (IFI27)

Homo sapiens — UniProt P40305

Gene: IFI27Homo sapiensSwissProt reviewed

About Interferon alpha-inducible protein 27, mitochondrial

Interferon alpha-inducible protein 27, mitochondrial (IFI27) is a protein from Homo sapiens identified by UniProt accession P40305, 122 residues long. MolForge cross-references it against 0 known binders and 244 disease associations.

Target properties

Protein nameInterferon alpha-inducible protein 27, mitochondrial
UniProt accessionP40305
GeneIFI27
OrganismHomo sapiens
Length122 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (244)

Diseases linked to this target (Open Targets).

  • blood protein measurement · score 0.14
  • COVID-19 · score 0.10
  • oral squamous cell carcinoma · score 0.09
  • cancer · score 0.09
  • hepatocellular carcinoma · score 0.08
  • breast cancer · score 0.08
  • pancreatic neoplasm · score 0.07
  • IGA glomerulonephritis · score 0.07
  • neoplasm · score 0.07
  • Systemic lupus erythematosus · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P40305-F1alphafoldPREDICTED53.63—

Amino-acid sequence (122 residues)

MEASALTSSA VTSVAKVVRV ASGSAVVLPL ARIATVVIGG VVAMAAVPMV LSAMGFTAAG IASSSIAAKM MSAAAIANGG GVASGSLVAT LQSLGATGLS GLTKFILGSI GSAIAAVIAR FY

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Quick facts

UniProtP40305
GeneIFI27
OrganismHomo sapiens
Length122
Binders0
Diseases244
View on UniProt