Chymotrypsin-like protease CTRL-1 (CTRL)

About Chymotrypsin-like protease CTRL-1

Chymotrypsin-like protease CTRL-1 (CTRL) is a protein from Homo sapiens identified by UniProt accession P40313, 264 residues long. MolForge cross-references it against 0 known binders and 151 disease associations.

Target properties

Protein name	Chymotrypsin-like protease CTRL-1
UniProt accession	P40313
Gene	CTRL
Organism	Homo sapiens
Length	264 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (151)

Diseases linked to this target (Open Targets).

erythrocyte count · score 0.21
mean corpuscular volume · score 0.17
red blood cell density measurement · score 0.12
mean corpuscular hemoglobin · score 0.10
high density lipoprotein cholesterol measurement · score 0.07
mathematical ability · score 0.07
refractive error · score 0.07
metabolic syndrome · score 0.06
triglyceride measurement · score 0.06
serum urea measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P40313-F1	alphafold	PREDICTED	91.03	—

Amino-acid sequence (264 residues)

MLLLSLTLSL VLLGSSWGCG IPAIKPALSF SQRIVNGENA VLGSWPWQVS LQDSSGFHFC GGSLISQSWV VTAAHCNVSP GRHFVVLGEY DRSSNAEPLQ VLSVSRAITH PSWNSTTMNN DVTLLKLASP AQYTTRISPV CLASSNEALT EGLTCVTTGW GRLSGVGNVT PAHLQQVALP LVTVNQCRQY WGSSITDSMI CAGGAGASSC QGDSGGPLVC QKGNTWVLIG IVSWGTKNCN VRAPAVYTRV SKFSTWINQV IAYN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards