About Large ribosomal subunit protein uL13
Large ribosomal subunit protein uL13 (RPL13A) is a protein
from Homo sapiens identified by UniProt accession
P40429, 203 residues long.
MolForge cross-references it against 0 known binders and
99 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein uL13 |
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| UniProt accession | P40429 |
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| Gene | RPL13A |
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| Organism | Homo sapiens |
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| Length | 203 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (99)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- neurodegenerative disease · score 0.46
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- glioblastoma multiforme · score 0.15
- aniridia · score 0.09
- monocyte count · score 0.09
- diffuse large B-cell lymphoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P40429-F1 | alphafold | PREDICTED | 95.76 | — |
Amino-acid sequence (203 residues)
MAEVQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLPH KTKRGQAALD RLKVFDGIPP PYDKKKRMVV PAALKVVRLK PTRKFAYLGR LAHEVGWKYQ AVTATLEEKR KEKAKIHYRK KKQLMRLRKQ AEKNVEKKID KYTEVLKTHG LLV
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