About ADP-ribosylation factor-like protein 4A
ADP-ribosylation factor-like protein 4A (ARL4A) is a protein
from Homo sapiens identified by UniProt accession
P40617, 200 residues long.
MolForge cross-references it against 0 known binders and
114 disease associations.
Target properties
| Protein name | ADP-ribosylation factor-like protein 4A |
|---|
| UniProt accession | P40617 |
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| Gene | ARL4A |
|---|
| Organism | Homo sapiens |
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| Length | 200 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (114)
Diseases linked to this target (Open Targets).
- cortical thickness · score 0.35
- hemoglobin measurement · score 0.29
- hematocrit · score 0.28
- red blood cell density measurement · score 0.27
- lymphocyte count · score 0.26
- drug use measurement · score 0.25
- adolescent idiopathic scoliosis · score 0.24
- metabolite measurement · score 0.21
- body height · score 0.20
- bone density · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P40617-F1 | alphafold | PREDICTED | 91.46 | — |
Amino-acid sequence (200 residues)
MGNGLSDQTS ILSNLPSFQS FHIVILGLDC AGKTTVLYRL QFNEFVNTVP TKGFNTEKIK VTLGNSKTVT FHFWDVGGQE KLRPLWKSYT RCTDGIVFVV DSVDVERMEE AKTELHKITR ISENQGVPVL IVANKQDLRN SLSLSEIEKL LAMGELSSST PWHLQPTCAI IGDGLKEGLE KLHDMIIKRR KMLRQQKKKR
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