Interleukin-15 (IL15)

About Interleukin-15

Interleukin-15 (IL15) is a protein from Homo sapiens identified by UniProt accession P40933, 162 residues long. MolForge cross-references it against 0 known binders and 926 disease associations.

Target properties

Protein name	Interleukin-15
UniProt accession	P40933
Gene	IL15
Organism	Homo sapiens
Length	162 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (926)

Diseases linked to this target (Open Targets).

neurofibrillary tangles measurement · score 0.39
leukocyte count · score 0.29
protein measurement · score 0.25
response to trauma exposure · score 0.20
post-traumatic stress disorder symptom measurement · score 0.20
breast milk measurement · score 0.19
neoplasm · score 0.12
cancer · score 0.11
Systemic lupus erythematosus · score 0.11
infection · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P40933-F1	alphafold	PREDICTED	84.66	—

Amino-acid sequence (162 residues)

MRISKPHLRS ISIQCYLCLL LNSHFLTEAG IHVFILGCFS AGLPKTEANW VNVISDLKKI EDLIQSMHID ATLYTESDVH PSCKVTAMKC FLLELQVISL ESGDASIHDT VENLIILANN SLSSNGNVTE SGCKECEELE EKNIKEFLQS FVHIVQMFIN TS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards