Replication factor C subunit 5 (RFC5)

About Replication factor C subunit 5

Replication factor C subunit 5 (RFC5) is a protein from Homo sapiens identified by UniProt accession P40937, 340 residues long. MolForge cross-references it against 0 known binders and 134 disease associations.

Target properties

Protein name	Replication factor C subunit 5
UniProt accession	P40937
Gene	RFC5
Organism	Homo sapiens
Length	340 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P40937-F1	alphafold	PREDICTED	90.46	—

Amino-acid sequence (340 residues)

METSALKQQE QPAATKIRNL PWVEKYRPQT LNDLISHQDI LSTIQKFINE DRLPHLLLYG PPGTGKTSTI LACAKQLYKD KEFGSMVLEL NASDDRGIDI IRGPILSFAS TRTIFKKGFK LVILDEADAM TQDAQNALRR VIEKFTENTR FCLICNYLSK IIPALQSRCT RFRFGPLTPE LMVPRLEHVV EEEKVDISED GMKALVTLSS GDMRRALNIL QSTNMAFGKV TEETVYTCTG HPLKSDIANI LDWMLNQDFT TAYRNITELK TLKGLALHDI LTEIHLFVHR VDFPSSVRIH LLTKMADIEY RLSVGTNEKI QLSSLIAAFQ VTRDLIVAEA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards