Replication factor C subunit 3 (RFC3)

About Replication factor C subunit 3

Replication factor C subunit 3 (RFC3) is a protein from Homo sapiens identified by UniProt accession P40938, 356 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

Target properties

Protein name	Replication factor C subunit 3
UniProt accession	P40938
Gene	RFC3
Organism	Homo sapiens
Length	356 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P40938-F1	alphafold	PREDICTED	87.49	—

Amino-acid sequence (356 residues)

MSLWVDKYRP CSLGRLDYHK EQAAQLRNLV QCGDFPHLLV YGPSGAGKKT RIMCILRELY GVGVEKLRIE HQTITTPSKK KIEISTIASN YHLEVNPSDA GNSDRVVIQE MLKTVAQSQQ LETNSQRDFK VVLLTEVDKL TKDAQHALRR TMEKYMSTCR LILCCNSTSK VIPPIRSRCL AVRVPAPSIE DICHVLSTVC KKEGLNLPSQ LAHRLAEKSC RNLRKALLMC EACRVQQYPF TADQEIPETD WEVYLRETAN AIVSQQTPQR LLEVRGRLYE LLTHCIPPEI IMKGLLSELL HNCDGQLKGE VAQMAAYYEH RLQLGSKAIY HLEAFVAKFM ALYKKFMEDG LEGMMF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards