About DNA-binding protein inhibitor ID-1
DNA-binding protein inhibitor ID-1 (ID1) is a protein
from Homo sapiens identified by UniProt accession
P41134, 155 residues long.
MolForge cross-references it against 0 known binders and
505 disease associations.
Target properties
| Protein name | DNA-binding protein inhibitor ID-1 |
|---|
| UniProt accession | P41134 |
|---|
| Gene | ID1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 155 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (505)
Diseases linked to this target (Open Targets).
- apolipoprotein A 1 measurement · score 0.26
- breast adenocarcinoma · score 0.25
- glioblastoma multiforme · score 0.24
- ovarian cancer · score 0.23
- head and neck squamous cell carcinoma · score 0.19
- endometrial cancer · score 0.18
- high density lipoprotein cholesterol measurement · score 0.17
- urinary bladder cancer · score 0.13
- triglyceride measurement · score 0.13
- hepatocellular carcinoma · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P41134-F1 | alphafold | PREDICTED | 65.49 | — |
Amino-acid sequence (155 residues)
MKVASGSTAT AAAGPSCALK AGKTASGAGE VVRCLSEQSV AISRCAGGAG ARLPALLDEQ QVNVLLYDMN GCYSRLKELV PTLPQNRKVS KVEILQHVID YIRDLQLELN SESEVGTPGG RGLPVRAPLS TLNGEISALT AEAACVPADD RILCR
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