About Centrin-2
Centrin-2 (CETN2) is a protein
from Homo sapiens identified by UniProt accession
P41208, 172 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | Centrin-2 |
|---|
| UniProt accession | P41208 |
|---|
| Gene | CETN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 172 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (72)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.26
- endometrial cancer · score 0.23
- esophageal cancer · score 0.14
- neurodegenerative disease · score 0.14
- esophageal squamous cell carcinoma · score 0.08
- glioblastoma multiforme · score 0.05
- hepatocellular carcinoma · score 0.03
- triple-negative breast cancer · score 0.02
- non-alcoholic fatty liver disease · score 0.02
- breast cancer · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P41208-F1 | alphafold | PREDICTED | 85.43 | — |
Amino-acid sequence (172 residues)
MASNFKKANM ASSSQRKRMS PKPELTEEQK QEIREAFDLF DADGTGTIDV KELKVAMRAL GFEPKKEEIK KMISEIDKEG TGKMNFGDFL TVMTQKMSEK DTKEEILKAF KLFDDDETGK ISFKNLKRVA KELGENLTDE ELQEMIDEAD RDGDGEVSEQ EFLRIMKKTS LY
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