Regulator of G-protein signaling 2 (RGS2)

About Regulator of G-protein signaling 2

Regulator of G-protein signaling 2 (RGS2) is a protein from Homo sapiens identified by UniProt accession P41220, 211 residues long. MolForge cross-references it against 0 known binders and 265 disease associations.

Target properties

Protein name	Regulator of G-protein signaling 2
UniProt accession	P41220
Gene	RGS2
Organism	Homo sapiens
Length	211 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P41220-F1	alphafold	PREDICTED	80.06	—

Amino-acid sequence (211 residues)

MQSAMFLAVQ HDCRPMDKSA GSGHKSEEKR EKMKRTLLKD WKTRLSYFLQ NSSTPGKPKT GKKSKQQAFI KPSPEEAQLW SEAFDELLAS KYGLAAFRAF LKSEFCEENI EFWLACEDFK KTKSPQKLSS KARKIYTDFI EKEAPKEINI DFQTKTLIAQ NIQEATSGCF TTAQKRVYSL MENNSYPRFL ESEFYQDLCK KPQITTEPHA T

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards