Protein BUD31 homolog (BUD31)

About Protein BUD31 homolog

Protein BUD31 homolog (BUD31) is a protein from Homo sapiens identified by UniProt accession P41223, 144 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Protein BUD31 homolog
UniProt accession	P41223
Gene	BUD31
Organism	Homo sapiens
Length	144 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
reticulocyte count · score 0.04
alcohol consumption measurement · score 0.04
platelet count · score 0.03
neoplasm · score 0.03
alcohol use disorder measurement · score 0.03
cancer · score 0.03
mean corpuscular volume · score 0.03
smoking status measurement · score 0.03
reticulocyte measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P41223-F1	alphafold	PREDICTED	90.77	—

Amino-acid sequence (144 residues)

MPKVKRSRKA PPDGWELIEP TLDELDQKMR EAETEPHEGK RKVESLWPIF RIHHQKTRYI FDLFYKRKAI SRELYEYCIK EGYADKNLIA KWKKQGYENL CCLRCIQTRD TNFGTNCICR VPKSKLEVGR IIECTHCGCR GCSG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards