N-alpha-acetyltransferase 10 (NAA10)

About N-alpha-acetyltransferase 10

N-alpha-acetyltransferase 10 (NAA10) is a protein from Homo sapiens identified by UniProt accession P41227, 235 residues long. MolForge cross-references it against 0 known binders and 170 disease associations.

Target properties

Protein name	N-alpha-acetyltransferase 10
UniProt accession	P41227
Gene	NAA10
Organism	Homo sapiens
Length	235 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (170)

Diseases linked to this target (Open Targets).

Ogden syndrome · score 0.80
Premature aging appearance-developmental delay-cardiac arrhythmia syndrome · score 0.73
Microphthalmia - ankyloblepharon - intellectual disability · score 0.64
Intellectual disability · score 0.49
genetic disorder · score 0.40
microphthalmia, Lenz type · score 0.37
NAA10-related syndrome · score 0.37
Intellectual disability, severe · score 0.34
Neurodevelopmental disorder · score 0.30
autism · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P41227-F1	alphafold	PREDICTED	80.33	—

Amino-acid sequence (235 residues)

MNIRNARPED LMNMQHCNLL CLPENYQMKY YFYHGLSWPQ LSYIAEDENG KIVGYVLAKM EEDPDDVPHG HITSLAVKRS HRRLGLAQKL MDQASRAMIE NFNAKYVSLH VRKSNRAALH LYSNTLNFQI SEVEPKYYAD GEDAYAMKRD LTQMADELRR HLELKEKGRH VVLGAIENKV ESKGNSPPSS GEACREEKGL AAEDSGGDSK DLSEVSETTE STDVKDSSEA SDSAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards