About Protein phosphatase inhibitor 2
Protein phosphatase inhibitor 2 (PPP1R2) is a protein
from Homo sapiens identified by UniProt accession
P41236, 205 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Protein phosphatase inhibitor 2 |
|---|
| UniProt accession | P41236 |
|---|
| Gene | PPP1R2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 205 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- neuroinflammatory disorder · score 0.26
- body height · score 0.07
- attention deficit hyperactivity disorder · score 0.06
- reticulocyte count · score 0.03
- lymphocyte count · score 0.03
- reticulocyte measurement · score 0.02
- lymphocyte percentage of leukocytes · score 0.02
- Abnormal sperm morphology · score 0.02
- Hyperphosphatemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P41236-F1 | alphafold | PREDICTED | 67.86 | — |
Amino-acid sequence (205 residues)
MAASTASHRP IKGILKNKTS TTSSMVASAE QPRGNVDEEL SKKSQKWDEM NILATYHPAD KDYGLMKIDE PSTPYHSMMG DDEDACSDTE ATEAMAPDIL ARKLAAAEGL EPKYRIQEQE SSGEEDSDLS PEEREKKRQF EMKRKLHYNE GLNIKLARQL ISKDLHDDDE DEEMLETADG ESMNTEESNQ GSTPSDQQQN KLRSS
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