About Folate receptor gamma
Folate receptor gamma (FOLR3) is a protein
from Homo sapiens identified by UniProt accession
P41439, 245 residues long.
MolForge cross-references it against 0 known binders and
70 disease associations.
Target properties
| Protein name | Folate receptor gamma |
|---|
| UniProt accession | P41439 |
|---|
| Gene | FOLR3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 245 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (70)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.39
- Parkinson disease · score 0.27
- Alzheimer disease · score 0.27
- multiple sclerosis · score 0.27
- lysosomal storage disease · score 0.27
- neuroinflammatory disorder · score 0.22
- influenza A (H1N1) · score 0.07
- calcium measurement · score 0.07
- lung adenocarcinoma · score 0.05
- urinary albumin to creatinine ratio · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P41439-F1 | alphafold | PREDICTED | 89.61 | — |
Amino-acid sequence (245 residues)
MDMAWQMMQL LLLALVTAAG SAQPRSARAR TDLLNVCMNA KHHKTQPSPE DELYGQCSPW KKNACCTAST SQELHKDTSR LYNFNWDHCG KMEPTCKRHF IQDSCLYECS PNLGPWIRQV NQSWRKERIL NVPLCKEDCE RWWEDCRTSY TCKSNWHKGW NWTSGINECP AGALCSTFES YFPTPAALCE GLWSHSFKVS NYSRGSGRCI QMWFDSAQGN PNEEVAKFYA AAMNAGAPSR GIIDS
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