About Tetraspanin-7
Tetraspanin-7 (TSPAN7) is a protein
from Homo sapiens identified by UniProt accession
P41732, 249 residues long.
MolForge cross-references it against 0 known binders and
128 disease associations.
Target properties
| Protein name | Tetraspanin-7 |
|---|
| UniProt accession | P41732 |
|---|
| Gene | TSPAN7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 249 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (128)
Diseases linked to this target (Open Targets).
- X-linked non-syndromic intellectual disability · score 0.66
- intellectual disability, X-linked 58 · score 0.62
- non-syndromic X-linked intellectual disability · score 0.18
- breast adenocarcinoma · score 0.18
- Intellectual disability · score 0.14
- cutaneous melanoma · score 0.10
- attention deficit hyperactivity disorder · score 0.10
- attention deficit-hyperactivity disorder 8 · score 0.09
- schizophrenia 15 · score 0.09
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P41732-F1 | alphafold | PREDICTED | 89.23 | — |
Amino-acid sequence (249 residues)
MASRRMETKP VITCLKTLLI IYSFVFWITG VILLAVGVWG KLTLGTYISL IAENSTNAPY VLIGTGTTIV VFGLFGCFAT CRGSPWMLKL YAMFLSLVFL AELVAGISGF VFRHEIKDTF LRTYTDAMQT YNGNDERSRA VDHVQRSLSC CGVQNYTNWS TSPYFLEHGI PPSCCMNETD CNPQDLHNLT VAATKVNQKG CYDLVTSFME TNMGIIAGVA FGIAFSQLIG MLLACCLSRF ITANQYEMV
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