Large ribosomal subunit protein uL29 (RPL35)

About Large ribosomal subunit protein uL29

Large ribosomal subunit protein uL29 (RPL35) is a protein from Homo sapiens identified by UniProt accession P42766, 123 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

Target properties

Protein name	Large ribosomal subunit protein uL29
UniProt accession	P42766
Gene	RPL35
Organism	Homo sapiens
Length	123 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (56)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
neurodegenerative disease · score 0.50
influenza · score 0.46
Blackfan-Diamond anemia · score 0.45
Diamond-Blackfan anemia · score 0.37
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P42766-F1	alphafold	PREDICTED	94.55	—

Amino-acid sequence (123 residues)

MAKIKARDLR GKKKEELLKQ LDDLKVELSQ LRVAKVTGGA ASKLSKIRVV RKSIARVLTV INQTQKENLR KFYKGKKYKP LDLRPKKTRA MRRRLNKHEE NLKTKKQQRK ERLYPLRKYA VKA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards