C-X-C motif chemokine 5 (CXCL5)

About C-X-C motif chemokine 5

C-X-C motif chemokine 5 (CXCL5) is a protein from Homo sapiens identified by UniProt accession P42830, 114 residues long. MolForge cross-references it against 0 known binders and 524 disease associations.

Target properties

Protein name	C-X-C motif chemokine 5
UniProt accession	P42830
Gene	CXCL5
Organism	Homo sapiens
Length	114 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (524)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.43
CXCL5 measurement · score 0.39
C-X-C motif chemokine 5 measurement · score 0.28
inflammatory bowel disease · score 0.21
neoplasm · score 0.12
hepatocellular carcinoma · score 0.11
cancer · score 0.10
gonorrhea · score 0.09
glioblastoma multiforme · score 0.09
pachyonychia congenita · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P42830-F1	alphafold	PREDICTED	80.67	—

Amino-acid sequence (114 residues)

MSLLSSRAAR VPGPSSSLCA LLVLLLLLTQ PGPIASAGPA AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKEN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards