Melanoma-associated antigen 11 (MAGEA11)

About Melanoma-associated antigen 11

Melanoma-associated antigen 11 (MAGEA11) is a protein from Homo sapiens identified by UniProt accession P43364, 429 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Melanoma-associated antigen 11
UniProt accession	P43364
Gene	MAGEA11
Organism	Homo sapiens
Length	429 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

esophageal squamous cell carcinoma · score 0.09
neoplasm · score 0.08
head and neck squamous cell carcinoma · score 0.08
polycystic ovary syndrome · score 0.07
breast cancer · score 0.04
renal cell carcinoma · score 0.03
gonorrhea · score 0.03
cancer · score 0.02
gastric adenocarcinoma · score 0.02
laryngeal squamous cell carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P43364-F1	alphafold	PREDICTED	63.08	—

Amino-acid sequence (429 residues)

METQFRRGGL GCSPASIKRK KKREDSGDFG LQVSTMFSED DFQSTERAPY GPQLQWSQDL PRVQVFREQA NLEDRSPRRT QRITGGEQVL WGPITQIFPT VRPADLTRVI MPLEQRSQHC KPEEGLQAQE EDLGLVGAQA LQAEEQEAAF FSSTLNVGTL EELPAAESPS PPQSPQEESF SPTAMDAIFG SLSDEGSGSQ EKEGPSTSPD LIDPESFSQD ILHDKIIDLV HLLLRKYRVK GLITKAEMLG SVIKNYEDYF PEIFREASVC MQLLFGIDVK EVDPTSHSYV LVTSLNLSYD GIQCNEQSMP KSGLLIIVLG VIFMEGNCIP EEVMWEVLSI MGVYAGREHF LFGEPKRLLT QNWVQEKYLV YRQVPGTDPA CYEFLWGPRA HAETSKMKVL EYIANANGRD PTSYPSLYED ALREEGEGV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards