Melanoma-associated antigen B1 (MAGEB1)

About Melanoma-associated antigen B1

Melanoma-associated antigen B1 (MAGEB1) is a protein from Homo sapiens identified by UniProt accession P43366, 347 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Melanoma-associated antigen B1
UniProt accession	P43366
Gene	MAGEB1
Organism	Homo sapiens
Length	347 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

calf circumference measurement · score 0.03
neoplasm · score 0.02
hepatocellular carcinoma · score 0.01
benign prostatic hyperplasia · score 0.01
non-small cell lung carcinoma · score 0.00
cancer · score 0.00
sarcoma · score 0.00
breast cancer · score 0.00
esophageal squamous cell carcinoma · score 0.00
Neoplasm of the lung · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P43366-F1	alphafold	PREDICTED	73.16	—

Amino-acid sequence (347 residues)

MPRGQKSKLR AREKRRKARE ETQGLKVAHA TAAEKEECPS SSPVLGDTPT SSPAAGIPQK PQGAPPTTTA AAAVSCTESD EGAKCQGEEN ASFSQATTST ESSVKDPVAW EAGMLMHFIL RKYKMREPIM KADMLKVVDE KYKDHFTEIL NGASRRLELV FGLDLKEDNP SGHTYTLVSK LNLTNDGNLS NDWDFPRNGL LMPLLGVIFL KGNSATEEEI WKFMNVLGAY DGEEHLIYGE PRKFITQDLV QEKYLKYEQV PNSDPPRYQF LWGPRAYAET TKMKVLEFLA KMNGATPRDF PSHYEEALRD EEERAQVRSS VRARRRTTAT TFRARSRAPF SRSSHPM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards