Ran-specific GTPase-activating protein (RANBP1)

Homo sapiens — UniProt P43487

Gene: RANBP1Homo sapiensSwissProt reviewed

About Ran-specific GTPase-activating protein

Ran-specific GTPase-activating protein (RANBP1) is a protein from Homo sapiens identified by UniProt accession P43487, 201 residues long. MolForge cross-references it against 0 known binders and 129 disease associations.

Target properties

Protein nameRan-specific GTPase-activating protein
UniProt accessionP43487
GeneRANBP1
OrganismHomo sapiens
Length201 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P43487-F1alphafoldPREDICTED83.36—

Amino-acid sequence (201 residues)

MAAAKDTHED HDTSTENTDE SNHDPQFEPI VSLPEQEIKT LEEDEEELFK MRAKLFRFAS ENDLPEWKER GTGDVKLLKH KEKGAIRLLM RRDKTLKICA NHYITPMMEL KPNAGSDRAW VWNTHADFAD ECPKPELLAI RFLNAENAQK FKTKFEECRK EIEEREKKAG SGKNDHAEKV AEKLEALSVK EETKEDAEEK Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

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Quick facts

UniProtP43487
GeneRANBP1
OrganismHomo sapiens
Length201
Binders0
Diseases129
View on UniProt