About Glutathione S-transferase Mu 5
Glutathione S-transferase Mu 5 (GSTM5) is a protein
from Homo sapiens identified by UniProt accession
P46439, 218 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Glutathione S-transferase Mu 5 |
|---|
| UniProt accession | P46439 |
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| Gene | GSTM5 |
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| Organism | Homo sapiens |
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| Length | 218 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.30
- protein measurement · score 0.30
- apolipoprotein A 1 measurement · score 0.29
- blood protein measurement · score 0.28
- mean platelet volume · score 0.12
- sex hormone-binding globulin measurement · score 0.12
- urinary bladder carcinoma · score 0.09
- monocyte count · score 0.08
- lung adenocarcinoma · score 0.07
- gonorrhea · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P46439-F1 | alphafold | PREDICTED | 97.29 | — |
Amino-acid sequence (218 residues)
MPMTLGYWDI RGLAHAIRLL LEYTDSSYVE KKYTLGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILRYI ARKHNLCGET EEEKIRVDIL ENQVMDNHME LVRLCYDPDF EKLKPKYLEE LPEKLKLYSE FLGKRPWFAG DKITFVDFLA YDVLDMKRIF EPKCLDAFLN LKDFISRFEG LKKISAYMKS SQFLRGLLFG KSATWNSK
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