About B1 bradykinin receptor
B1 bradykinin receptor (BDKRB1) is a protein
from Homo sapiens identified by UniProt accession
P46663, 353 residues long.
MolForge cross-references it against 0 known binders and
234 disease associations.
Target properties
| Protein name | B1 bradykinin receptor |
|---|
| UniProt accession | P46663 |
|---|
| Gene | BDKRB1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 353 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (234)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.29
- ovarian cancer · score 0.26
- breast adenocarcinoma · score 0.25
- head and neck squamous cell carcinoma · score 0.16
- prostate adenocarcinoma · score 0.10
- angioedema · score 0.09
- neoplasm · score 0.09
- response to angiotensin-converting enzyme inhibitor · score 0.09
- osteoarthritis · score 0.09
- experimental autoimmune encephalomyelitis · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P46663-F1 | alphafold | PREDICTED | 85.11 | — |
Amino-acid sequence (353 residues)
MASSWPPLEL QSSNQSQLFP QNATACDNAP EAWDLLHRVL PTFIISICFF GLLGNLFVLL VFLLPRRQLN VAEIYLANLA ASDLVFVLGL PFWAENIWNQ FNWPFGALLC RVINGVIKAN LFISIFLVVA ISQDRYRVLV HPMASRRQQR RRQARVTCVL IWVVGGLLSI PTFLLRSIQA VPDLNITACI LLLPHEAWHF ARIVELNILG FLLPLAAIVF FNYHILASLR TREEVSRTRC GGRKDSKTTA LILTLVVAFL VCWAPYHFFA FLEFLFQVQA VRGCFWEDFI DLGLQLANFF AFTNSSLNPV IYVFVGRLFR TKVWELYKQC TPKSLAPISS SHRKEIFQLF WRN
Explore B1 bradykinin receptor with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets