Large ribosomal subunit protein eL28 (RPL28)

About Large ribosomal subunit protein eL28

Large ribosomal subunit protein eL28 (RPL28) is a protein from Homo sapiens identified by UniProt accession P46779, 137 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL28
UniProt accession	P46779
Gene	RPL28
Organism	Homo sapiens
Length	137 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Becker muscular dystrophy · score 0.29
clear cell renal carcinoma · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26
neurodegenerative disease · score 0.20
white matter microstructure measurement · score 0.17
body height · score 0.10
aniridia · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P46779-F1	alphafold	PREDICTED	92.68	—

Amino-acid sequence (137 residues)

MSAHLQWMVV RNCSSFLIKR NKQTYSTEPN NLKARNSFRY NGLIHRKTVG VEPAADGKGV VVVIKRRSGQ RKPATSYVRT TINKNARATL SSIRHMIRKN KYRPDLRMAA IRRASAILRS QKPVMVKRKR TRPTKSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards