About Small ribosomal subunit protein uS4
Small ribosomal subunit protein uS4 (RPS9) is a protein
from Homo sapiens identified by UniProt accession
P46781, 194 residues long.
MolForge cross-references it against 0 known binders and
77 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein uS4 |
|---|
| UniProt accession | P46781 |
|---|
| Gene | RPS9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 194 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (77)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- COVID-19 · score 0.37
- severe acute respiratory syndrome · score 0.37
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- Takayasu arteritis · score 0.22
- alkaline phosphatase measurement · score 0.16
- blood protein measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P46781-F1 | alphafold | PREDICTED | 88.12 | — |
Amino-acid sequence (194 residues)
MPVARSWVCR KTYVTPRRPF EKSRLDQELK LIGEYGLRNK REVWRVKFTL AKIRKAAREL LTLDEKDPRR LFEGNALLRR LVRIGVLDEG KMKLDYILGL KIEDFLERRL QTQVFKLGLA KSIHHARVLI RQRHIRVRKQ VVNIPSFIVR LDSQKHIDFS LRSPYGGGRP GRVKRKNAKK GQGGAGAGDD EEED
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