Small ribosomal subunit protein uS7 (RPS5)

Homo sapiens — UniProt P46782

Gene: RPS5Homo sapiensSwissProt reviewed

About Small ribosomal subunit protein uS7

Small ribosomal subunit protein uS7 (RPS5) is a protein from Homo sapiens identified by UniProt accession P46782, 204 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.

Target properties

Protein nameSmall ribosomal subunit protein uS7
UniProt accessionP46782
GeneRPS5
OrganismHomo sapiens
Length204 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (73)

Diseases linked to this target (Open Targets).

  • Duchenne muscular dystrophy · score 0.50
  • cystic fibrosis · score 0.50
  • influenza · score 0.46
  • COVID-19 · score 0.37
  • severe acute respiratory syndrome · score 0.37
  • Becker muscular dystrophy · score 0.29
  • qualitative or quantitative defects of dystrophin · score 0.26
  • neurodegenerative disease · score 0.22
  • glioblastoma multiforme · score 0.15
  • aniridia · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P46782-F1alphafoldPREDICTED90.41—

Amino-acid sequence (204 residues)

MTEWETAAPA VAETPDIKLF GKWSTDDVQI NDISLQDYIA VKEKYAKYLP HSAGRYAAKR FRKAQCPIVE RLTNSMMMHG RNNGKKLMTV RIVKHAFEII HLLTGENPLQ VLVNAIINSG PREDSTRIGR AGTVRRQAVD VSPLRRVNQA IWLLCTGARE AAFRNIKTIA ECLADELINA AKGSSNSYAI KKKDELERVA KSNR

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Quick facts

UniProtP46782
GeneRPS5
OrganismHomo sapiens
Length204
Binders0
Diseases73
View on UniProt