About Small ribosomal subunit protein uS7
Small ribosomal subunit protein uS7 (RPS5) is a protein
from Homo sapiens identified by UniProt accession
P46782, 204 residues long.
MolForge cross-references it against 0 known binders and
73 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein uS7 |
| UniProt accession | P46782 |
| Gene | RPS5 |
| Organism | Homo sapiens |
| Length | 204 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (73)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- COVID-19 · score 0.37
- severe acute respiratory syndrome · score 0.37
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- neurodegenerative disease · score 0.22
- glioblastoma multiforme · score 0.15
- aniridia · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P46782-F1 | alphafold | PREDICTED | 90.41 | — |
Amino-acid sequence (204 residues)
MTEWETAAPA VAETPDIKLF GKWSTDDVQI NDISLQDYIA VKEKYAKYLP HSAGRYAAKR FRKAQCPIVE RLTNSMMMHG RNNGKKLMTV RIVKHAFEII HLLTGENPLQ VLVNAIINSG PREDSTRIGR AGTVRRQAVD VSPLRRVNQA IWLLCTGARE AAFRNIKTIA ECLADELINA AKGSSNSYAI KKKDELERVA KSNR
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