Small ribosomal subunit protein eS10 (RPS10)

About Small ribosomal subunit protein eS10

Small ribosomal subunit protein eS10 (RPS10) is a protein from Homo sapiens identified by UniProt accession P46783, 165 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.

Target properties

Protein name	Small ribosomal subunit protein eS10
UniProt accession	P46783
Gene	RPS10
Organism	Homo sapiens
Length	165 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (73)

Diseases linked to this target (Open Targets).

Diamond-Blackfan anemia · score 0.76
Blackfan-Diamond anemia · score 0.76
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
COVID-19 · score 0.37
Abnormal radial ray morphology · score 0.37
severe acute respiratory syndrome · score 0.37
Becker muscular dystrophy · score 0.29
endometrial cancer · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P46783-F1	alphafold	PREDICTED	73.84	—

Amino-acid sequence (165 residues)

MLMPKKNRIA IYELLFKEGV MVAKKDVHMP KHPELADKNV PNLHVMKAMQ SLKSRGYVKE QFAWRHFYWY LTNEGIQYLR DYLHLPPEIV PATLRRSRPE TGRPRPKGLE GERPARLTRG EADRDTYRRS AVPPGADKKA EAGAGSATEF QFRGGFGRGR GQPPQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards