Alpha-S1-casein (CSN1S1)

About Alpha-S1-casein

Alpha-S1-casein (CSN1S1) is a protein from Homo sapiens identified by UniProt accession P47710, 185 residues long. MolForge cross-references it against 0 known binders and 109 disease associations.

Target properties

Protein name	Alpha-S1-casein
UniProt accession	P47710
Gene	CSN1S1
Organism	Homo sapiens
Length	185 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (109)

Diseases linked to this target (Open Targets).

breast cancer · score 0.08
cancer · score 0.07
prurigo · score 0.05
neurodermatitis · score 0.05
Helicobacter pylori infectious disease · score 0.03
neoplasm · score 0.02
obstructive sleep apnea · score 0.02
pulse pressure measurement · score 0.02
Invasive Breast Carcinoma · score 0.02
triple-negative breast cancer · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P47710-F1	alphafold	PREDICTED	62.54	—

Amino-acid sequence (185 residues)

MRLLILTCLV AVALARPKLP LRYPERLQNP SESSEPIPLE SREEYMNGMN RQRNILREKQ TDEIKDTRNE STQNCVVAEP EKMESSISSS SEEMSLSKCA EQFCRLNEYN QLQLQAAHAQ EQIRRMNENS HVQVPFQQLN QLAAYPYAVW YYPQIMQYVP FPPFSDISNP TAHENYEKNN VMLQW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards