RPE-retinal G protein-coupled receptor (RGR)

About RPE-retinal G protein-coupled receptor

RPE-retinal G protein-coupled receptor (RGR) is a protein from Homo sapiens identified by UniProt accession P47804, 291 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	RPE-retinal G protein-coupled receptor
UniProt accession	P47804
Gene	RGR
Organism	Homo sapiens
Length	291 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P47804-F1	alphafold	PREDICTED	90.26	—

Amino-acid sequence (291 residues)

MAETSALPTG FGELEVLAVG MVLLVEALSG LSLNTLTIFS FCKTPELRTP CHLLVLSLAL ADSGISLNAL VAATSSLLRR WPYGSDGCQA HGFQGFVTAL ASICSSAAIA WGRYHHYCTR SQLAWNSAVS LVLFVWLSSA FWAALPLLGW GHYDYEPLGT CCTLDYSKGD RNFTSFLFTM SFFNFAMPLF ITITSYSLME QKLGKSGHLQ VNTTLPARTL LLGWGPYAIL YLYAVIADVT SISPKLQMVP ALIAKMVPTI NAINYALGNE MVCRGIWQCL SPQKREKDRT K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards