About Olfactory receptor 3A1
Olfactory receptor 3A1 (OR3A1) is a protein
from Homo sapiens identified by UniProt accession
P47881, 315 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Olfactory receptor 3A1 |
| UniProt accession | P47881 |
| Gene | OR3A1 |
| Organism | Homo sapiens |
| Length | 315 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- clear cell renal carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- colorectal adenocarcinoma · score 0.05
- non-small cell lung carcinoma · score 0.03
- adolescent idiopathic scoliosis · score 0.02
- diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P47881-F1 | alphafold | PREDICTED | 86.85 | — |
Amino-acid sequence (315 residues)
MQPESGANGT VIAEFILLGL LEAPGLQPVV FVLFLFAYLV TVRGNLSILA AVLVEPKLHT PMYFFLGNLS VLDVGCISVT VPSMLSRLLS RKRAVPCGAC LTQLFFFHLF VGVDCFLLTA MAYDRFLAIC RPLTYSTRMS QTVQRMLVAA SWACAFTNAL THTVAMSTLN FCGPNVINHF YCDLPQLFQL SCSSTQLNEL LLFAVGFIMA GTPMALIVIS YIHVAAAVLR IRSVEGRKKA FSTCGSHLTV VAIFYGSGIF NYMRLGSTKL SDKDKAVGIF NTVINPMLNP IIYSFRNPDV QSAIWRMLTG RRSLA
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