About Large ribosomal subunit protein eL29
Large ribosomal subunit protein eL29 (RPL29) is a protein
from Homo sapiens identified by UniProt accession
P47914, 159 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein eL29 |
|---|
| UniProt accession | P47914 |
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| Gene | RPL29 |
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| Organism | Homo sapiens |
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| Length | 159 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (63)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- neurodegenerative disease · score 0.42
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- self reported educational attainment · score 0.13
- low density lipoprotein cholesterol measurement · score 0.10
- aniridia · score 0.09
- diffuse large B-cell lymphoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P47914-F1 | alphafold | PREDICTED | 81.45 | — |
Amino-acid sequence (159 residues)
MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMSARAE AIKALVKPKE VKPKIPKGVS RKLDRLAYIA HPKLGKRARA RIAKGLRLCR PKAKAKAKAK DQTKAQAAAP ASVPAQAPKR TQAPTKASE
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