DNA-binding protein inhibitor ID-4 (ID4)

About DNA-binding protein inhibitor ID-4

DNA-binding protein inhibitor ID-4 (ID4) is a protein from Homo sapiens identified by UniProt accession P47928, 161 residues long. MolForge cross-references it against 0 known binders and 218 disease associations.

Target properties

Protein name	DNA-binding protein inhibitor ID-4
UniProt accession	P47928
Gene	ID4
Organism	Homo sapiens
Length	161 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (218)

Diseases linked to this target (Open Targets).

lean body mass · score 0.51
body height · score 0.50
fat body mass · score 0.48
forced expiratory volume · score 0.47
body fat distribution · score 0.46
vital capacity · score 0.45
body weight · score 0.44
chronic obstructive pulmonary disease · score 0.44
appendicular lean mass · score 0.44
BMI-adjusted waist circumference · score 0.44

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P47928-F1	alphafold	PREDICTED	66.28	—

Amino-acid sequence (161 residues)

MKAVSPVRPS GRKAPSGCGG GELALRCLAE HGHSLGGSAA AAAAAAAARC KAAEAAADEP ALCLQCDMND CYSRLRRLVP TIPPNKKVSK VEILQHVIDY ILDLQLALET HPALLRQPPP PAPPHHPAGT CPAAPPRTPL TALNTDPAGA VNKQGDSILC R

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards