Galectin-7 (LGALS7)

About Galectin-7

Galectin-7 (LGALS7) is a protein from Homo sapiens identified by UniProt accession P47929, 136 residues long. MolForge cross-references it against 0 known binders and 139 disease associations.

Target properties

Protein name	Galectin-7
UniProt accession	P47929
Gene	LGALS7
Organism	Homo sapiens
Length	136 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (139)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
neoplasm · score 0.11
head and neck squamous cell carcinoma · score 0.08
esophageal squamous cell carcinoma · score 0.08
melanoma · score 0.07
oral squamous cell carcinoma · score 0.07
platelet count · score 0.06
drug use measurement · score 0.06
nonpapillary renal cell carcinoma · score 0.05
breast cancer · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P47929-F1	alphafold	PREDICTED	96.62	—

Amino-acid sequence (136 residues)

MSNVPHKSSL PEGIRPGTVL RIRGLVPPNA SRFHVNLLCG EEQGSDAALH FNPRLDTSEV VFNSKEQGSW GREERGPGVP FQRGQPFEVL IIASDDGFKA VVGDAQYHHF RHRLPLARVR LVEVGGDVQL DSVRIF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards