Lymphotactin (XCL1)

About Lymphotactin

Lymphotactin (XCL1) is a protein from Homo sapiens identified by UniProt accession P47992, 114 residues long. MolForge cross-references it against 0 known binders and 195 disease associations.

Target properties

Protein name	Lymphotactin
UniProt accession	P47992
Gene	XCL1
Organism	Homo sapiens
Length	114 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (195)

Diseases linked to this target (Open Targets).

adolescent idiopathic scoliosis · score 0.27
glioblastoma multiforme · score 0.26
breast adenocarcinoma · score 0.25
head and neck squamous cell carcinoma · score 0.16
electrocardiography · score 0.15
low grade glioma · score 0.14
Hepatitis · score 0.11
neoplasm · score 0.10
prostate adenocarcinoma · score 0.10
disease free survival · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P47992-F1	alphafold	PREDICTED	78.81	—

Amino-acid sequence (114 residues)

MRLLILALLG ICSLTAYIVE GVGSEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards