Carboxypeptidase A2 (CPA2)

About Carboxypeptidase A2

Carboxypeptidase A2 (CPA2) is a protein from Homo sapiens identified by UniProt accession P48052, 419 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

Target properties

Protein name	Carboxypeptidase A2
UniProt accession	P48052
Gene	CPA2
Organism	Homo sapiens
Length	419 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (69)

Diseases linked to this target (Open Targets).

drug use measurement · score 0.08
Female infertility due to fertilization defect · score 0.06
hereditary hyperferritinemia with congenital cataracts · score 0.05
femoral hernia · score 0.05
blood protein measurement · score 0.05
gastric carcinoma · score 0.05
Cataract-microcornea syndrome · score 0.05
female infertility due to oocyte meiotic arrest · score 0.05
Hydatidiform Mole · score 0.04
premature ovarian failure 19 · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P48052-F1	alphafold	PREDICTED	95.04	—

Amino-acid sequence (419 residues)

MAMRLILFFG ALFGHIYCLE TFVGDQVLEI VPSNEEQIKN LLQLEAQEHL QLDFWKSPTT PGETAHVRVP FVNVQAVKVF LESQGIAYSI MIEDVQVLLD KENEEMLFNR RRERSGNFNF GAYHTLEEIS QEMDNLVAEH PGLVSKVNIG SSFENRPMNV LKFSTGGDKP AIWLDAGIHA REWVTQATAL WTANKIVSDY GKDPSITSIL DALDIFLLPV TNPDGYVFSQ TKNRMWRKTR SKVSGSLCVG VDPNRNWDAG FGGPGASSNP CSDSYHGPSA NSEVEVKSIV DFIKSHGKVK AFITLHSYSQ LLMFPYGYKC TKLDDFDELS EVAQKAAQSL RSLHGTKYKV GPICSVIYQA SGGSIDWSYD YGIKYSFAFE LRDTGRYGFL LPARQILPTA EETWLGLKAI MEHVRDHPY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards