About Glioma pathogenesis-related protein 1
Glioma pathogenesis-related protein 1 (GLIPR1) is a protein
from Homo sapiens identified by UniProt accession
P48060, 266 residues long.
MolForge cross-references it against 0 known binders and
87 disease associations.
Target properties
| Protein name | Glioma pathogenesis-related protein 1 |
|---|
| UniProt accession | P48060 |
|---|
| Gene | GLIPR1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 266 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (87)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.30
- bone density · score 0.30
- age at menopause · score 0.20
- cup-to-disc ratio measurement · score 0.15
- polycystic ovary syndrome · score 0.11
- intrathoracic organ injury · score 0.11
- neoplasm · score 0.09
- glioblastoma multiforme · score 0.09
- melanoma · score 0.08
- metabolite measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P48060-F1 | alphafold | PREDICTED | 87.09 | — |
Amino-acid sequence (266 residues)
MRVTLATIAW MVSFVSNYSH TANILPDIEN EDFIKDCVRI HNKFRSEVKP TASDMLYMTW DPALAQIAKA WASNCQFSHN TRLKPPHKLH PNFTSLGENI WTGSVPIFSV SSAITNWYDE IQDYDFKTRI CKKVCGHYTQ VVWADSYKVG CAVQFCPKVS GFDALSNGAH FICNYGPGGN YPTWPYKRGA TCSACPNNDK CLDNLCVNRQ RDQVKRYYSV VYPGWPIYPR NRYTSLFLIV NSVILILSVI ITILVQHKYP NLVLLD
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