ATP synthase F(0) complex subunit C3, mitochondrial…

About ATP synthase F(0) complex subunit C3, mitochondrial

ATP synthase F(0) complex subunit C3, mitochondrial (ATP5MC3) is a protein from Homo sapiens identified by UniProt accession P48201, 142 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	ATP synthase F(0) complex subunit C3, mitochondrial
UniProt accession	P48201
Gene	ATP5MC3
Organism	Homo sapiens
Length	142 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

vital capacity · score 0.27
self reported educational attainment · score 0.24
systolic blood pressure · score 0.20
genetic disorder · score 0.18
muscular dystrophy · score 0.17
lung adenocarcinoma · score 0.08
body fat percentage · score 0.07
resting heart rate · score 0.06
PHF-tau measurement · score 0.06
arterial stiffness measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P48201-F1	alphafold	PREDICTED	71.59	—

Amino-acid sequence (142 residues)

MFACAKLACT PSLIRAGSRV AYRPISASVL SRPEASRTGE GSTVFNGAQN GVSQLIQREF QTSAISRDID TAAKFIGAGA ATVGVAGSGA GIGTVFGSLI IGYARNPSLK QQLFSYAILG FALSEAMGLF CLMVAFLILF AM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

ATP synthase F(0) complex subunit C3, mitochondrial (ATP5MC3)