About CD151 antigen
CD151 antigen (CD151) is a protein
from Homo sapiens identified by UniProt accession
P48509, 253 residues long.
MolForge cross-references it against 0 known binders and
330 disease associations.
Target properties
| Protein name | CD151 antigen |
|---|
| UniProt accession | P48509 |
|---|
| Gene | CD151 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 253 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (330)
Diseases linked to this target (Open Targets).
- Nephrotic syndrome-deafness-pretibial epidermolysis bullosa syndrome · score 0.72
- epidermolysis bullosa simplex 7, with nephropathy and deafness · score 0.66
- mean platelet volume · score 0.23
- platelet count · score 0.19
- genetic disorder · score 0.18
- pulse pressure measurement · score 0.12
- neoplasm · score 0.12
- hepatocellular carcinoma · score 0.11
- clear cell renal carcinoma · score 0.10
- cancer · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P48509-F1 | alphafold | PREDICTED | 88.27 | — |
Amino-acid sequence (253 residues)
MGEFNEKKTT CGTVCLKYLL FTYNCCFWLA GLAVMAVGIW TLALKSDYIS LLASGTYLAT AYILVVAGTV VMVTGVLGCC ATFKERRNLL RLYFILLLII FLLEIIAGIL AYAYYQQLNT ELKENLKDTM TKRYHQPGHE AVTSAVDQLQ QEFHCCGSNN SQDWRDSEWI RSQEAGGRVV PDSCCKTVVA LCGQRDHASN IYKVEGGCIT KLETFIQEHL RVIGAVGIGI ACVQVFGMIF TCCLYRSLKL EHY
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