About Protein PRRC2A
Protein PRRC2A (PRRC2A) is a protein
from Homo sapiens identified by UniProt accession
P48634, 2157 residues long.
MolForge cross-references it against 0 known binders and
110 disease associations.
Target properties
| Protein name | Protein PRRC2A |
|---|
| UniProt accession | P48634 |
|---|
| Gene | PRRC2A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 2157 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (110)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- monocyte count · score 0.28
- body fat percentage · score 0.18
- grip strength measurement · score 0.17
- systolic blood pressure · score 0.17
- body height · score 0.17
- sex hormone-binding globulin measurement · score 0.16
- waist circumference · score 0.14
- age at menopause · score 0.14
- visceral adipose tissue measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P48634-F1 | alphafold | PREDICTED | 39.75 | — |
Amino-acid sequence (2157 residues)
MSDRSGPTAK GKDGKKYSSL NLFDTYKGKS LEIQKPAVAP RHGLQSLGKV AIARRMPPPA NLPSLKAENK GNDPNVSLVP KDGTGWASKQ EQSDPKSSDA STAQPPESQP LPASQTPASN QPKRPPAAPE NTPLVPSGVK SWAQASVTHG AHGDGGRASS LLSRFSREEF PTLQAAGDQD KAAKERESAE QSSGPGPSLR PQNSTTWRDG GGRGPDELEG PDSKLHHGHD PRGGLQPSGP PQFPPYRGMM PPFMYPPYLP FPPPYGPQGP YRYPTPDGPS RFPRVAGPRG SGPPMRLVEP VGRPSILKED NLKEFDQLDQ ENDDGWAGAH EEVDYTEKLK FSDEEDGRDS DEEGAEGHRD SQSASGEERP PEADGKKGNS PNSEPPTPKT AWAETSRPPE TEPGPPAPKP PLPPPHRGPA GNWGPPGDYP DRGGPPCKPP APEDEDEAWR QRRKQSSSEI SLAVERARRR REEEERRMQE ERRAACAEKL KRLDEKFGAP DKRLKAEPAA PPAAPSTPAP PPAVPKELPA PPAPPPASAP TPETEPEEPA QAPPAQSTPT PGVAAAPTLV SGGGSTSSTS SGSFEASPVE PQLPSKEGPE PPEEVPPPTT PPVPKVEPKG DGIGPTRQPP SQGLGYPKYQ KSLPPRFQRQ QQEQLLKQQQ QHQWQQHQQG SAPPTPVPPS PPQPVTLGAV PAPQAPPPPP KALYPGALGR PPPMPPMNFD PRWMMIPPYV DPRLLQGRPP LDFYPPGVHP SGLVPRERSD SGGSSSEPFD RHAPAMLRER GTPPVDPKLA WVGDVFTATP AEPRPLTSPL RQAADEDDKG MRSETPPVPP PPPYLASYPG FPENGAPGPP ISRFPLEEPG PRPLPWPPGS DEVAKIQTPP PKKEPPKEET AQLTGPEAGR KPARGVGSGG QGPPPPRRES RTETRWGPRP GSSRRGIPPE EPGAPPRRAG PIKKPPPPTK VEELPPKPLE QGDETPKPPK PDPLKITKGK LGGPKETPPN GNLSPAPRLR RDYSYERVGP TSCRGRGRGE YFARGRGFRG TYGGRGRGAR SREFRSYREF RGDDGRGGGT GGPNHPPAPR GRTASETRSE GSEYEEIPKR RRQRGSETGS ETHESDLAPS DKEAPTPKEG TLTQVPLAPP PPGAPPSPAP ARFTARGGRV FTPRGVPSRR GRGGGRPPPQ VCPGWSPPAK SLAPKKPPTG PLPPSKEPLK EKLIPGPLSP VARGGSNGGS NVGMEDGERP RRRRHGRAQQ QDKPPRFRRL KQERENAARG SEGKPSLTLP ASAPGPEEAL TTVTVAPAPR RAAAKSPDLS NQNSDQANEE WETASESSDF TSERRGDKEA PPPVLLTPKA VGTPGGGGGG AVPGISAMSR GDLSQRAKDL SKRSFSSQRP GMERQNRRPG PGGKAGSSGS SSGGGGGGPG GRTGPGRGDK RSWPSPKNRS RPPEERPPGL PLPPPPPSSS AVFRLDQVIH SNPAGIQQAL AQLSSRQGSV TAPGGHPRHK PGLPQAPQGP SPRPPTRYEP QRVNSGLSSD PHFEEPGPMV RGVGGTPRDS AGVSPFPPKR RERPPRKPEL LQEESLPPPH SSGFLGSKPE GPGPQAESRD TGTEALTPHI WNRLHTATSR KSYRPSSMEP WMEPLSPFED VAGTEMSQSD SGVDLSGDSQ VSSGPCSQRS SPDGGLKGAA EGPPKRPGGS SPLNAVPCEG PPGSEPPRRP PPAPHDGDRK ELPREQPLPP GPIGTERSQR TDRGTEPGPI RPSHRPGPPV QFGTSDKDSD LRLVVGDSLK AEKELTASVT EAIPVSRDWE LLPSAAASAE PQSKNLDSGH CVPEPSSSGQ RLYPEVFYGS AGPSSSQISG GAMDSQLHPN SGGFRPGTPS LHPYRSQPLY LPPGPAPPSA LLSGLALKGQ FLDFSTMQAT ELGKLPAGGV LYPPPSFLYS PAFCPSPLPD TSLLQVRQDL PSPSDFYSTP LQPGGQSGFL PSGAPAQQML LPMVDSQLPV VNFGSLPPAP PPAPPPLSLL PVGPALQPPS LAVRPPPAPA TRVLPSPARP FPASLGRAEL HPVELKPFQD YQKLSSNLGG PGSSRTPPTG RSFSGLNSRL KATPSTYSGV FRTQRVDLYQ QASPPDALRW IPKPWERTGP PPREGPSRRA EEPGSRGDKE PGLPPPR
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