Heat shock 70 kDa protein 13 (HSPA13)

About Heat shock 70 kDa protein 13

Heat shock 70 kDa protein 13 (HSPA13) is a protein from Homo sapiens identified by UniProt accession P48723, 471 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Heat shock 70 kDa protein 13
UniProt accession	P48723
Gene	HSPA13
Organism	Homo sapiens
Length	471 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

diffuse plaque measurement · score 0.23
breast adenocarcinoma · score 0.18
pancreatic adenocarcinoma · score 0.10
hepatocellular carcinoma · score 0.08
Systemic lupus erythematosus · score 0.04
Miyoshi myopathy · score 0.03
neoplasm · score 0.03
drug use measurement · score 0.02
visual perception measurement · score 0.02
dengue disease · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P48723-F1	alphafold	PREDICTED	87.38	—

Amino-acid sequence (471 residues)

MAREMTILGS AVLTLLLAGY LAQQYLPLPT PKVIGIDLGT TYCSVGVFFP GTGKVKVIPD ENGHISIPSM VSFTDNDVYV GYESVELADS NPQNTIYDAK RFIGKIFTAE ELEAEIGRYP FKVLNKNGMV EFSVTSNETI TVSPEYVGSR LLLKLKEMAE AYLGMPVANA VISVPAEFDL KQRNSTIEAA NLAGLKILRV INEPTAAAMA YGLHKADVFH VLVIDLGGGT LDVSLLNKQG GMFLTRAMSG NNKLGGQDFN QRLLQYLYKQ IYQTYGFVPS RKEEIHRLRQ AVEMVKLNLT LHQSAQLSVL LTVEEQDRKE PHSSDTELPK DKLSSADDHR VNSGFGRGLS DKKSGESQVL FETEISRKLF DTLNEDLFQK ILVPIQQVLK EGHLEKTEID EVVLVGGSTR IPRIRQVIQE FFGKDPNTSV DPDLAVVTGV AIQAGIDGGS WPLQVSALEI PNKHLQKTNF N

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards