Large ribosomal subunit protein eL34 (RPL34)

About Large ribosomal subunit protein eL34

Large ribosomal subunit protein eL34 (RPL34) is a protein from Homo sapiens identified by UniProt accession P49207, 117 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL34
UniProt accession	P49207
Gene	RPL34
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (75)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
hair color · score 0.29
Becker muscular dystrophy · score 0.29
clear cell renal carcinoma · score 0.27
body height · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26
hair colour measurement · score 0.23
vital capacity · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P49207-F1	alphafold	PREDICTED	90.36	—

Amino-acid sequence (117 residues)

MVQRLTYRRR LSYNTASNKT RLSRTPGNRI VYLYTKKVGK APKSACGVCP GRLRGVRAVR PKVLMRLSKT KKHVSRAYGG SMCAKCVRDR IKRAFLIEEQ KIVVKVLKAQ AQSQKAK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards