About Large ribosomal subunit protein bL19m
Large ribosomal subunit protein bL19m (MRPL19) is a protein
from Homo sapiens identified by UniProt accession
P49406, 292 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein bL19m |
|---|
| UniProt accession | P49406 |
|---|
| Gene | MRPL19 |
|---|
| Organism | Homo sapiens |
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| Length | 292 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (37)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- lung adenocarcinoma · score 0.07
- chronotype measurement · score 0.05
- hippocampal atrophy · score 0.04
- schizophrenia · score 0.04
- reaction time measurement · score 0.03
- cancer · score 0.02
- neoplasm · score 0.02
- dyslexia · score 0.01
- myeloid sarcoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P49406-F1 | alphafold | PREDICTED | 83.89 | — |
Amino-acid sequence (292 residues)
MAACIAAGHW AAMGLGRSFQ AARTLLPPPA SIACRVHAGP VRQQSTGPSE PGAFQPPPKP VIVDKHRPVE PERRFLSPEF IPRRGRTDPL KFQIERKDML ERRKVLHIPE FYVGSILRVT TADPYASGKI SQFLGICIQR SGRGLGATFI LRNVIEGQGV EICFELYNPR VQEIQVVKLE KRLDDSLLYL RDALPEYSTF DVNMKPVVQE PNQKVPVNEL KVKMKPKPWS KRWERPNFNI KGIRFDLCLT EQQMKEAQKW NQPWLEFDMM REYDTSKIEA AIWKEIEASK RS
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