CCAAT/enhancer-binding protein delta (CEBPD)

About CCAAT/enhancer-binding protein delta

CCAAT/enhancer-binding protein delta (CEBPD) is a protein from Homo sapiens identified by UniProt accession P49716, 269 residues long. MolForge cross-references it against 0 known binders and 260 disease associations.

Target properties

Protein name	CCAAT/enhancer-binding protein delta
UniProt accession	P49716
Gene	CEBPD
Organism	Homo sapiens
Length	269 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (260)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.45
monocyte count · score 0.45
monocyte percentage of leukocytes · score 0.41
basophil count · score 0.41
eosinophil percentage of leukocytes · score 0.40
neutrophil count · score 0.40
neutrophil percentage of leukocytes · score 0.40
infectious disease · score 0.37
viral disease · score 0.37
neuroinflammatory disorder · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P49716-F1	alphafold	PREDICTED	65.13	—

Amino-acid sequence (269 residues)

MSAALFSLDG PARGAPWPAE PAPFYEPGRA GKPGRGAEPG ALGEPGAAAP AMYDDESAID FSAYIDSMAA VPTLELCHDE LFADLFNSNH KAGGAGPLEL LPGGPARPLG PGPAAPRLLK REPDWGDGDA PGSLLPAQVA ACAQTVVSLA AAGQPTPPTS PEPPRSSPRQ TPAPGPAREK SAGKRGPDRG SPEYRQRRER NNIAVRKSRD KAKRRNQEMQ QKLVELSAEN EKLHQRVEQL TRDLAGLRQF FKQLPSPPFL PAAGTADCR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards