Regulator of G-protein signaling 4 (RGS4)

Homo sapiens — UniProt P49798

Gene: RGS4Homo sapiensSwissProt reviewed

About Regulator of G-protein signaling 4

Regulator of G-protein signaling 4 (RGS4) is a protein from Homo sapiens identified by UniProt accession P49798, 205 residues long. MolForge cross-references it against 0 known binders and 247 disease associations.

Target properties

Protein nameRegulator of G-protein signaling 4
UniProt accessionP49798
GeneRGS4
OrganismHomo sapiens
Length205 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P49798-F1alphafoldPREDICTED78.86—

Amino-acid sequence (205 residues)

MCKGLAGLPA SCLRSAKDMK HRLGFLLQKS DSCEHNSSHN KKDKVVICQR VSQEEVKKWA ESLENLISHE CGLAAFKAFL KSEYSEENID FWISCEEYKK IKSPSKLSPK AKKIYNEFIS VQATKEVNLD SCTREETSRN MLEPTITCFD EAQKKIFNLM EKDSYRRFLK SRFYLDLVNP SSCGAEKQKG AKSSADCASL VPQCA

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Quick facts

UniProtP49798
GeneRGS4
OrganismHomo sapiens
Length205
Binders0
Diseases247
View on UniProt