About Kallikrein-7
Kallikrein-7 (KLK7) is a protein
from Homo sapiens identified by UniProt accession
P49862, 253 residues long.
MolForge cross-references it against 0 known binders and
105 disease associations.
Target properties
| Protein name | Kallikrein-7 |
|---|
| UniProt accession | P49862 |
|---|
| Gene | KLK7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 253 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (105)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.37
- kallikrein-7 measurement · score 0.26
- neurodegenerative disease · score 0.24
- breast adenocarcinoma · score 0.22
- neoplasm · score 0.07
- oral squamous cell carcinoma · score 0.06
- pancreatic neoplasm · score 0.05
- benign prostatic hyperplasia · score 0.05
- central nervous system cancer · score 0.05
- kallikrein‐6 measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P49862-F1 | alphafold | PREDICTED | 91.57 | — |
Amino-acid sequence (253 residues)
MARSLLLPLQ ILLLSLALET AGEEAQGDKI IDGAPCARGS HPWQVALLSG NQLHCGGVLV NERWVLTAAH CKMNEYTVHL GSDTLGDRRA QRIKASKSFR HPGYSTQTHV NDLMLVKLNS QARLSSMVKK VRLPSRCEPP GTTCTVSGWG TTTSPDVTFP SDLMCVDVKL ISPQDCTKVY KDLLENSMLC AGIPDSKKNA CNGDSGGPLV CRGTLQGLVS WGTFPCGQPN DPGVYTQVCK FTKWINDTMK KHR
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