About Zincore component SEPHS1
Zincore component SEPHS1 (SEPHS1) is a protein
from Homo sapiens identified by UniProt accession
P49903, 392 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Zincore component SEPHS1 |
|---|
| UniProt accession | P49903 |
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| Gene | SEPHS1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 392 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (36)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- sex hormone-binding globulin measurement · score 0.30
- Abdominal symptom · score 0.27
- Neurodevelopmental disorder · score 0.19
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.08
- microphthalmia with limb anomalies · score 0.06
- cancer · score 0.04
- diastolic blood pressure · score 0.03
- blood urea nitrogen measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P49903-F1 | alphafold | PREDICTED | 89.61 | — |
Amino-acid sequence (392 residues)
MSTRESFNPE SYELDKSFRL TRFTELKGTG CKVPQDVLQK LLESLQENHF QEDEQFLGAV MPRLGIGMDT CVIPLRHGGL SLVQTTDYIY PIVDDPYMMG RIACANVLSD LYAMGVTECD NMLMLLGVSN KMTDRERDKV MPLIIQGFKD AAEEAGTSVT GGQTVLNPWI VLGGVATTVC QPNEFIMPDN AVPGDVLVLT KPLGTQVAVA VHQWLDIPEK WNKIKLVVTQ EDVELAYQEA MMNMARLNRT AAGLMHTFNA HAATDITGFG ILGHAQNLAK QQRNEVSFVI HNLPVLAKMA AVSKACGNMF GLMHGTCPET SGGLLICLPR EQAARFCAEI KSPKYGEGHQ AWIIGIVEKG NRTARIIDKP RIIEVAPQVA TQNVNPTPGA TS
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